Hot Papers

Biomimetic Hierarchical Construction of Anti-Tumor Polyoxopalladates for Cancer Therapy

Zhao, Y.; Liu, Z.; Qin, Z.; Wen, Q.; Du, J.; Ren, X.-Y.; Chen, C.-Q.; Peng, X.; Kortz, U.; Yang, P. Angew. Chem. Int. Ed. 2025, e202505564. [Read Online]

Engineering of lacunary polyoxopalladates resulted in a hierarchical assembly that resembles the construction of biomacromolecules. An ordered structural evolution from monomer via dimer to supramolecular aggregates was achieved by cooperative covalent and supramolecular bonding effects, resulting in enhanced anti-tumor activity via DNA damage.

 

 

 

Noble Metalate Bowl: The Polyoxo-6-Vanado(V)-7-Palladate(II) [Pd₇V₆O₂₄(OH)₂]^6-

Izarova, N. V.; Vankova, N.; Banerjee, A.; Jameson, G. B.; Heine, T.; Schinle, F.; Hampe, O.; Kortz, U. Angew. Chem. Int. Ed. 2010, 49, 7807-7811. [Read Online]

Nobly born: The bowl-shaped noble metalate [Pd^II₇V^V₆O₂₄(OH)₂]⁶⁻(Pd₇V₆) comprises seven square-planar Pd^IIO₄ units as well as four tetrahedral V^VO₄ and two square-pyramidal V^VO₅ addenda units (see picture). The solution stability of Pd₇V₆ has been demonstrated by ⁵¹V NMR spectroscopy, ESI mass spectrometry, and DFT calculations.

 

 

 

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